WebbBAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B /TACI, TNFRSF17 /BCMA, and TNFRSF13C … Webb27 apr. 2024 · BAFF levels have been associated with the clinical activity of SLE in humans. BAFF plays a pathogenic role in SLE in part through T cell-dependent B cell autoantibody production. BAFF, has a role in the maintenance of memory B cells and promotes plasma cell survival. Treatment strategies involving BAFF blockade haven been studied in …
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WebbPE anti-human CD257 (BAFF, BLYS) Antibody - The T7-241 antibody recognizes human BAFF also known as B cell activating factor, tumor necrosis factor ligand superfamily 13B, B lymphocyte stimulator (BLYS), TNF and APOL-related leukocyte expressed ligand 1 (TALL1), and TNF homolog that activates apoptosis, NF-κB, and JNK (THANK). WebbTarget Information. BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T … crimes.police go.kr
Human BAFF (BLyS) Recombinant Protein (PHC1674) - Thermo …
Webb23 mars 2024 · BAFF is expressed by cells of myeloid origin and by stromal cells 10. It binds to three receptors, BAFF receptor (BAFFR, TNFRSF13C), TACI, and B cell maturation antigen (BCMA, TNFRSF17), while... Webb1 feb. 2024 · The TNF superfamily ligand BAFF maintains the survival of naive B cells by signaling through its surface receptor, BAFFR. Activated B cells maintain expression of … Webb6 sep. 2024 · 206 Doaa S. D. Zaki et al.: Study of B Cell Activating Factor (BAFF) and BAFF-R in Systemic Lupus Erythematosus Patients The median and interquartile range (IQR) level of serum BAFF in SLE patients was significantly higher compared to healthy controls; 0.65 (0.38 – 1) ng/ml versus 0.25 (0.17 – اسم ترکی با سه