WebOct 18, 2024 · Phenytoin (Monograph) Brand names: Dilantin, Dilantin Infatabs, Phenytek Drug class: Hydantoins VA class: CN400 CAS number: 57-41-0 Medically reviewed by Drugs.com on Oct 18, 2024. Written by ASHP. Introduction Uses Dosage Warnings Interactions Stability Warning Cardiovascular Risk Associated with Rapid IV Administration WebFeb 17, 2024 · Patient Education Boxed Warning Cardiovascular risk associated with rapid infusion (injection): The rate of intravenous phenytoin administration should not exceed 50 mg/minute in adults and 1 to 3 mg/kg/minute (or 50 mg/minute, whichever is slower) in pediatric patients because of the risk of severe hypotension and cardiac arrhythmias.
Warfarin Drug Interactions - StatPearls - NCBI Bookshelf
http://www.drugebook.com/phenytoin/patient-education WebMay 8, 2024 · Continuing Education Activity. Warfarin has FDA approval for the prophylaxis and treatment of venous thrombosis and its complications, such as a pulmonary embolus. ... Long-term phenytoin use with warfarin can decrease the INR since it is a CYP inducer. Rifampin is also a CYP enzyme inducer. Due to the increase in warfarin metabolism, a … gifting bitcoin
Phenytoin Side Effects, Dosage, Uses, and More - Healthline
WebJul 11, 2024 · Phenytoin is a medication used in the management and treatment of epilepsy, generalized tonic-clonic seizures, complex partial seizures, and status epilepticus. It is in the anticonvulsants class of drugs. This activity describes the indications, action, and contraindications for phenytoin as a valuable agent in the treatment of epilepsy. WebMar 21, 2024 · Risk Summary: Prenatal exposure to this drug may increase the risks for major congenital malformations and other adverse developmental outcomes; children exposed to this drug in utero, alone or in combination with other antiepileptic drugs, have experienced fetal hydantoin syndrome. WebMay 1, 2006 · Phenytoin is 80% to 90% bound to albumin. 2 A significant clinical interaction can occur when drugs with narrow therapeutic indexes and high protein binding are displaced from binding sites. Perhaps the most important example of this mechanism for phenytoin-drug interactions is an initial transient increase in the effect of warfarin. 3 fs708tl