WebThe lncRNA nuclear enriched abundant transcript 1 (NEAT1) promotes sepsis-inflammatory responses and acute kidney injury (AKI), but little known about the underlying mechanisms. This study aims to investigate the roles of NEAT1 in regulating macrophage polarization and its potential for alleviating … WebSep 26, 2024 · NEAT1 is one of the most abundant, well-studied arcRNAs and thus is an ideal model for arcRNAs that trigger phase separation upon their expression. This SAM …
The Mechanism of lncRNA NEAT1 in Alleviating Acute Respiratory …
WebJan 3, 2024 · Cardiac fibrosis, a well-known major pathological process that ultimately leads to heart failure, has attracted increasing attention and focus in recent years. A large amount of research indicates that long noncoding RNAs (lncRNAs) play an important role in cardiac fibrosis, but little is known about the specific function and mechanism of the lncRNA … WebMay 2, 2024 · Neat1 is only highly expressed in certain adult mouse tissues, including the corpus luteum and developing mammary glands. ... as shown by genome-wide CHART-seq 109 and RAP-seq studies 110 (Table 1 ... flowers and wine
Genome-wide screening of NEAT1 regulators reveals …
WebApr 17, 2024 · Combining the enrichment of NEAT1 by CHART with deep sequencing, West and colleagues could show that NEAT1 localises to hundreds of actively transcribed protein-coding gene loci in MCF-7 cells. The accumulation of NEAT1 on chromatin is particularly strong at transcription start sites and transcription exit sites, and comprises significant ... WebJun 26, 2024 · CHART-mass spectrometry assays identified a large number of NEAT1-interacting proteins 66, suggesting that the function of NEAT1 in transcriptional … WebSep 5, 2024 · NEAT1 is upregulated in human CRC tissues and is associated with a poor prognosis in CRC patients To investigate the clinical significance of NEAT1, we analyzed its expression levels in the publicly available TCGA dataset … green and white mini specialists east rainton